Skip to main content
FSCDR's 17th Annual SCD Research and Educational Symposium & 46th Nat'l SCD Scientific Meeting Main banner
Icon Legend
This session is not in your schedule.
This session is in your schedule. Click again to remove it.
Presentation Icons
Live Stream
Live Stream
Back

Kalpna Gupta, PhD

Professor of Medicine
University of California, Irvine
University of California, Irvine
Long Beach, California, United States

Kalpna Gupta is a Professor and Susan Samueli Scholar for Integrative Health in the Department of Medicine, Division of Hematology/Oncology at the University of California, Irvine, CA. Her multidisciplinary translational research has led pioneering work on the neurovascular and neuroimmune mechanisms of opioid activity and pain. She described the first intracellular signaling pathway of morphine leading to cancer progression. She developed models for devastating acute and chronic sickle cell pain leading to the understanding of the peripheral and central mechanisms of pain in sickle cell disease (SCD). She has identified several new targets at the intersection of disease process and pain, including cannabinoid receptors, mast cells, neutrophils and the nociceptin receptor, in addition to integrative approaches including diet modification, acupuncture and perception modulation to relieve pain. Additionally, her laboratory is engaged in mechanisms of cancer pain and chemotherapy-induced peripheral neuropathy. wound healing, hemophilia pain and Alzheimer’s disease. Her multiple collaborations include those with engineers to develop qEEG for the quantitation of pain without bias and non-invasive transcranial focused ultrasound to treat pain. Dr Gupta is a recipient of the Excellence in Hemoglobinopathies Research Award from NHLBI to examine the potential of cannabinoids to treat SCD pain through preclinical studies and clinical trial. She has served as an advisor to the SCD program at NHLBI/NIH. She is deeply engaged in trainee advancement to gain independence and promoting diversity. She is a member of the Diversity and Equity Initiative of the American Society of Hematology.

Disclosure information not submitted.

Presentation(s):